• Categories: Scientific ArticlesBy 0.9 min read

    For at least 60 years it has been erroneously established that high blood cholesterol, associated with saturated fat intake, is responsible for heart disease. For this reason, millions of people around the world, under medical advice, resort to statin therapy. In line with official guidelines, the use of statins is aimed at controlling the plasma cholesterol level, especially of the Low Density Lipoprotein (LDL) fraction, supposedly to decrease the incidence of cardiovascular diseases and deaths. However, data from several meta-analyses of randomized controlled and observational trials conducted over the last few decades have failed to demonstrate that reducing saturated fat intake is actually beneficial in lowering cholesterol. Furthermore, there is no statistical correlation and causality between high cholesterol and cardiovascular disease. In addition, while many scientific articles highlight the safety of statins, others point to their many side effects, calling into question the validation of their use. This review presents and discusses the potential side effects of statins, as well as other important issues related to this therapeutic procedure.

  • Categories: Scientific ArticlesBy 1 min read

    Alzheimer's disease is a common cause of dementia in the elderly, characterized by neuropsychiatric symptoms related to neuroanatomical and biochemical changes in the cerebral cortex. Drug treatment has little efficacy in more advanced stages of the disease, which leads to the search for adjunctive resources. The endocannabinoid system has gained great scientific prominence as a therapeutic target in the treatment of Alzheimer's disease, its components being highly associated with the pathophysiology of the disease. The purpose of this.....

  • Categories: Scientific ArticlesBy 0.9 min read

    This is the fourth review article in the series that aims to break the paradigms related to the possible harm caused by saturated fats and cholesterol in human health. Topics are presented on the excessive intake of carbohydrates (sugars), considered to be the cause of organ imbalances and obesity, which lead to metabolic diseases such as cardiovascular diseases, type 2 diabetes, and hepatic steatosis, and worsen with metabolic syndrome and its comorbidities. Traditionally, obesity...

  • Categories: Scientific ArticlesBy 0.9 min read

    This is the third review article in the series that aims to break the paradigms related to the possible harm caused by saturated fats and cholesterol in human health. Scientific data on omega-6, omega-3, and trans fats and the phenomenon of lipid peroxidation are presented and discussed, as well as their influence on chronic inflammation. It has been wrongly established in recent decades that saturated fats and cholesterol are the cause of cardiovascular and related diseases. A new scientific theory, however, holds that these diseases...

  • Categories: Scientific ArticlesBy 0.7 min read

    This is the second article in the series that aims to break the paradigms related to the supposed harm caused by saturated fats and cholesterol to health. These substances, in fact, are present in human biochemistry and physiology, a fact that makes them essential for homeostasis. In case of intake deficit, they are produced endogenously, as they participate in numerous organic reactions, including structuring, fluidity and permeabilization of cell membranes, brain plasticity, nerve protection and communication, hormone formation[...].